What is Trabecular Meshwork? - Glaucoma Glossary

The Trabecular Meshwork is the spongy, sieve-like tissue located around the base of the cornea, responsible for draining the aqueous humor from the eye into the bloodstream.

What it means for the patient

Think of this as the main drain filter of your eye. In the most common form of glaucoma, this filter gets clogged or stiff over time, preventing fluid from leaving the eye properly.

Clinical significance

Increased resistance to aqueous outflow through the juxtacanalicular portion of the trabecular meshwork is the primary pathophysiological driver of primary open-angle glaucoma (POAG).

How it is tracked

Its anatomical status is evaluated via gonioscopy, and its functional capacity is assessed by IOP response to therapies like Selective Laser Trabeculoplasty (SLT).